Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases

Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases

ABSTRACT Denosumab has been used successfully to treat disease‐associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central giant cell granuloma (CGCG), aneurysma...

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Bibliographic Details
Main Authors: Alexander Upfill‐Brown, Susan Bukata, Nicholas M Bernthal, Alan L Felsenfeld, Scott D Nelson, Arun Singh, Katherine Wesseling‐Perry, Fritz C Eilber, Noah C Federman
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:JBMR Plus
Subjects:
Osteoclasts
Denosumab
RANKL
Hypercalcemia
Oncology
Online Access:https://doi.org/10.1002/jbm4.10210

Internet

https://doi.org/10.1002/jbm4.10210

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