Detectable chromosome X mosaicism in males is rarely tolerated in peripheral leukocytes

Abstract Age-related male Y and female X chromosome mosaicism is commonly observed in large population-based studies. To investigate the frequency of male X chromosome mosaicism, we scanned for deviations in chromosome X genotyping array intensity data in a population-based survey of 196,219 UK Biob...

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Bibliographic Details
Main Authors: Weiyin Zhou, Shu-Hong Lin, Sairah M. Khan, Meredith Yeager, Stephen J. Chanock, Mitchell J. Machiela
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80948-0