Insulin receptor endocytosis in the pathophysiology of insulin resistance

Insulin: Keeping the receptors signaling A potential cancer treatment also shows promise for treatment of type 2 diabetes. When insulin receptors (IRs) on cell surfaces bind to insulin, they send out signals that trigger glucose uptake, lowering blood sugar. The duration of IR signaling is crucial f...

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Bibliographic Details
Main Authors: Catherine Hall, Hongtao Yu, Eunhee Choi
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0456-3