Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway

Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway

Lung cancer is the major cause of cancer-associated death worldwide, and development of new therapeutic drugs is needed to improve treatment outcomes. Three-dimensional (3D) tumorspheroids offer many advantages over conventional two-dimensional cell cultures due to the similarities to in vivo tumors...

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Bibliographic Details
Main Authors: Ji Hae Lee, So-Young Park, Wonbin Hwang, Jee Young Sung, Myoung-Lae Cho Jaegal Shim, Yong-Nyun Kim, Kyungsil Yoon
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomolecules
Subjects:
isoharringtonine
NR4A1
apoptosis
tumorspheroids
NSCLC
Online Access:https://www.mdpi.com/2218-273X/10/11/1521

Internet

https://www.mdpi.com/2218-273X/10/11/1521

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