Uniform silica coated fluorescent nanoparticles: synthetic method, improved light stability and application to visualize lymph network tracer.

BACKGROUND: The sentinel lymph node biopsy (SLNB) was developed as a new modality in the surgical diagnosis of lymph node metastases. Dye and radioisotope are major tracers for the detection of sentinel lymph nodes (SLN). Dye tends to excessively infiltrate into the interstitium due to their small s...

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Bibliographic Details
Main Authors: Liman Cong, Motohiro Takeda, Yohei Hamanaka, Kohsuke Gonda, Mika Watanabe, Masutaka Kumasaka, Yoshio Kobayashi, Masaki Kobayashi, Noriaki Ohuchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2956628?pdf=render