Distinct Expression Profiles and Novel Targets of MicroRNAs in Human Spermatogonia, Pachytene Spermatocytes, and Round Spermatids between OA Patients and NOA Patients

Distinct Expression Profiles and Novel Targets of MicroRNAs in Human Spermatogonia, Pachytene Spermatocytes, and Round Spermatids between OA Patients and NOA Patients

Human spermatogenesis includes three main stages, namely, the mitosis of spermatogonia, meiosis of spermatocytes, and spermiogenesis of spermatids, which are precisely regulated by epigenetic and genetic factors. Abnormality of epigenetic and genetic factors can result in aberrant spermatogenesis an...

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Bibliographic Details
Main Authors: Chencheng Yao, Qingqing Yuan, Minghui Niu, Hongyong Fu, Fan Zhou, Wenhui Zhang, Hong Wang, Liping Wen, Ligang Wu, Zheng Li, Zuping He
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
microRNAs
human spermatogonia
pachytene spermatocytes
round spermatids
targeting genes
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117302573

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http://www.sciencedirect.com/science/article/pii/S2162253117302573

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