Role of an indole-thiazolidine molecule PPAR pan-agonist and COX inhibitor on inflammation and microcirculatory damage in acute gastric lesions.

Role of an indole-thiazolidine molecule PPAR pan-agonist and COX inhibitor on inflammation and microcirculatory damage in acute gastric lesions.

The present study aimed to show the in vivo mechanisms of action of an indole-thiazolidine molecule peroxisome-proliferator activated receptor pan-agonist (PPAR pan) and cyclooxygenase (COX) inhibitor, LYSO-7, in an ethanol/HCl-induced (Et/HCl) gastric lesion model. Swiss male mice were treated with...

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Bibliographic Details
Main Authors: José Roberto Santin, Isabel Daufenback Machado, Stephen F P Rodrigues, Simone Teixeira, Marcelo N Muscará, Suely Lins Galdino, Ivan da Rocha Pitta, Sandra H P Farsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790743?pdf=render

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http://europepmc.org/articles/PMC3790743?pdf=render

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