miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis

miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis

Abstract Background Increasing evidence indicates that epithelial-mesenchymal transition (EMT) can be regulated by microRNAs (miRNAs). miR-615-3p was shown to be involved in tumor development. However, the role of miR-615-3p in the metastasis of breast cancer remains largely unknown. Methods The exp...

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Bibliographic Details
Main Authors: Bo Lei, Dandan Wang, Ming Zhang, Yuwei Deng, Huijie Jiang, Yiwen Li
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-615-3p
EMT
TGF-β
PICK1
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13046-020-01571-5

Internet

http://link.springer.com/article/10.1186/s13046-020-01571-5

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