Cardioprotective Effect of Grape Seed Extract on Chronic Doxorubicin-Induced Cardiac Toxicity in Wistar Rats

Cardioprotective Effect of Grape Seed Extract on Chronic Doxorubicin-Induced Cardiac Toxicity in Wistar Rats

Purpose: The aim of the present study was to determine the ability of grape seed extract (GSE) as a powerful antioxidant in preventing adverse effect of doxorubicin (DOX) on heart function. Methods: Male rats were divided into three groups: control, DOX (2 mg/kg/48h, for 12 days) and GSE (100 mg/kg/...

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Bibliographic Details
Main Authors: Nasser Razmaraii, Hossein Babaei, Alireza Mohajjel Nayebi, Gholamreza Assadnassab, Javad Ashrafi Helan, Yadollah Azarmi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2016-09-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Grape Seed Extract
Cardioprotective
Doxorubicin
Cardiotoxicity
Cancer
ECG
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-423.pdf

Internet

http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-423.pdf

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