Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection

Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection

Despite evidence of augmented Natural Killer (NK) cell responses after influenza vaccination, the role of these cells in vaccine-induced immunity remains unclear. Here, we hypothesized that NK cells might increase viral clearance but possibly at the expense of increased severity of pathology. On the...

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Bibliographic Details
Main Authors: Jason P. Mooney, Tedi Qendro, Marianne Keith, Adrian W. Philbey, Helen T. Groves, John S. Tregoning, Martin R. Goodier, Eleanor M. Riley
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
NK cell
influenza
lung
vaccine
diphtheria toxin
mice
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00135/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00135/full

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