Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.

Many natural prion diseases of humans and animals are considered to be acquired through oral consumption of contaminated food or pasture. Determining the route by which prions establish host infection will identify the important factors that influence oral prion disease susceptibility and to which i...

Full description

Bibliographic Details
Main Authors: David S Donaldson, Anuj Sehgal, Daniel Rios, Ifor R Williams, Neil A Mabbott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5156364?pdf=render