Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR

DmpR is a bacterial enhancer binding protein from the AAA+ family of ATPases that binds aromatic compounds and controls the transcription of genes involved in the degradation of toxic pollutants. Here, the authors present the crystal structure of phenol-bound DmpR, which forms a tetramer and discuss...

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Bibliographic Details
Main Authors: Kwang-Hyun Park, Sungchul Kim, Su-Jin Lee, Jee-Eun Cho, Vinod Vikas Patil, Arti Baban Dumbrepatil, Hyung-Nam Song, Woo-Chan Ahn, Chirlmin Joo, Seung-Goo Lee, Victoria Shingler, Eui-Jeon Woo
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16562-5