HPV-Mediated Resistance to TNF and TRAIL Is Characterized by Global Alterations in Apoptosis Regulatory Factors, Dysregulation of Death Receptors, and Induction of ROS/RNS

Persistent infection with high-risk human papilloma virus (HR-HPV) is the main risk factor for the development of invasive cervical cancer although is not sufficient to cause cervical cancer. Several host and environmental factors play a key role in cancer initiation/progression, including cytokines...

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Bibliographic Details
Main Authors: Tatiane Karen Cabeça, Alice de Mello Abreu, Rafael Andrette, Vanesca de Souza Lino, Mirian Galliote Morale, Francisco Aguayo, Lara Termini, Luisa Lina Villa, Ana Paula Lepique, Enrique Boccardo
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
HPV
TNF
Online Access:http://www.mdpi.com/1422-0067/20/1/198