A common limiter circuit for opioid choice and relapse identified in a rodent addiction model

The neural circuits underlying rewarding effects of drugs of abuse and natural rewards are not fully understood. Here the authors investigate the role of the infralimbic cortex to nucleus accumbens shell pathway during heroin or food choice in rats.

Bibliographic Details
Main Authors: Jasper A. Heinsbroek, Giuseppe Giannotti, Mitchel R. Mandel, Megan Josey, Gary Aston-Jones, Morgan H. James, Jamie Peters
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25080-x