Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology

Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology

Models of Tau pathology related to frontotemporal dementia (FTD) are essential to determine underlying neurodegenerative pathologies and resulting tauopathy relevant behavioural changes. However, existing models are often limited in their translational value due to Tau overexpression, and the freque...

Full description

Bibliographic Details
Main Authors: David J. Koss, Lianne Robinson, Benjamin D. Drever, Kaja Plucińska, Sandra Stoppelkamp, Peter Veselcic, Gernot Riedel, Bettina Platt
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Neurobiology of Disease
Subjects:
Frontotemporal dementia
Tauopathies
Tau
Phosphorylation
Cognition
Apathy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300468

Internet

http://www.sciencedirect.com/science/article/pii/S0969996116300468

Similar Items