The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain

<p>Abstract</p> <p>Background</p> <p>High-mobility group box-1 protein (HMGB1) is a nuclear protein that regulates gene expression throughout the body. It can also become cytoplasmic and function as a neuromodulatory cytokine after tissue damage or injury. The manner in...

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Bibliographic Details
Main Authors: Feldman Polina, Due Michael R, Ripsch Matthew S, Khanna Rajesh, White Fletcher A
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/180