Amyloid Beta and Tau Proteins as Therapeutic Targets for Alzheimer’s Disease Treatment: Rethinking the Current Strategy

Alzheimer’s disease (AD) is defined by the concurrence of accumulation of abnormal aggregates composed of two proteins: Amyloid beta (Aβ) and tau, and of cellular changes including neurite degeneration and loss of neurons and cognitive functions. Based on their strong association with disease, genet...

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Bibliographic Details
Main Authors: Siddhartha Mondragón-Rodríguez, George Perry, Xiongwei Zhu, Jannic Boehm
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.1155/2012/630182