The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin.

The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin.

Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin disease resulting in non-healing wounds affecting body areas of high hair follicle and sweat gland density. The pathogenesis of HS is not well understood but appears to involve dysbiosis-driven aberrant activation of the innat...

Full description

Bibliographic Details
Main Authors: Margaret Coates, Paula Mariottoni, David L Corcoran, Hélène Fradin Kirshner, Tarannum Jaleel, David A Brown, Stephen R Brooks, John Murray, Maria I Morasso, Amanda S MacLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216249

Internet

https://doi.org/10.1371/journal.pone.0216249

Similar Items