Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

The steps from HIV-1 cytoplasmic entry until integration of the reverse transcribed genome are currently enigmatic. They occur in ill-defined reverse-transcription- and pre-integration-complexes (RTC, PIC) with various host and viral proteins implicated. In this study, we report quantitative detecti...

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Bibliographic Details
Main Authors: Ke Peng, Walter Muranyi, Bärbel Glass, Vibor Laketa, Stephen R Yant, Luong Tsai, Tomas Cihlar, Barbara Müller, Hans-Georg Kräusslich
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
HIV
viral entry
reverse transcription
macrophage
CPSF6
Online Access:https://elifesciences.org/articles/04114

Internet

https://elifesciences.org/articles/04114

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