RAP1 GTPase overexpression is associated with cervical intraepithelial neoplasia.

RAP1 GTPase overexpression is associated with cervical intraepithelial neoplasia.

RAP1 (RAS proximate 1), a small GTP-binding protein of the RAS superfamily, is a putative oncogene that is highly expressed in several malignant cell lines and types of cancers, including some types of squamous cell carcinoma. However, the participation of RAP1 in cervical carcinogenesis is unknown....

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Main Authors: Marcelo Antonio Pascoal-Xavier, Anna Carolina Cançado Figueiredo, Luciana Inácia Gomes, Vanessa Peruhype-Magalhães, Carlos Eduardo Calzavara-Silva, Marcelo Azevedo Costa, Ilka Afonso Reis, Claudio Antônio Bonjardim, Erna Geessien Kroon, Jaquelline G de Oliveira, Paulo César Peregrino Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4391937?pdf=render

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http://europepmc.org/articles/PMC4391937?pdf=render

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