NFAT1 and NFAT2 Differentially Regulate CTL Differentiation Upon Acute Viral Infection

NFAT1 and NFAT2 Differentially Regulate CTL Differentiation Upon Acute Viral Infection

CD8+ T cell differentiation orchestrated by transcription regulators is critical for balancing pathogen eradication and long-term immunity by effector and memory CTLs, respectively. The transcription factor Nuclear Factor of Activated T cells (NFAT) family members are known for their roles in T cell...

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Bibliographic Details
Main Authors: Tianhao Xu, Ashleigh Keller, Gustavo J. Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
NFAT1
NFAT2
CD8+ T cells
differentiation
effector
memory
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00184/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00184/full

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