Cyclin D1 + large B-cell lymphoma with altered CCND1 and BCL-6 rearrangements: a diagnostic challenge

Abstract Background A subset of diffuse large B-cell lymphoma may show aberrant cyclin D1 expression, which may be confused with blastoid mantle cell lymphoma. These cases usually lack of CCND1 gene rearrangement. Duplication of CCND1 gene was attributed to some of the cases with cyclin D1 expressio...

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Bibliographic Details
Main Authors: Da Gao, Zach Liu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Biomarker Research
Subjects:
MCL
Online Access:http://link.springer.com/article/10.1186/s40364-019-0162-2