Burkholderia pseudomallei invades the olfactory nerve and bulb after epithelial injury in mice and causes the formation of multinucleated giant glial cells in vitro.

Burkholderia pseudomallei invades the olfactory nerve and bulb after epithelial injury in mice and causes the formation of multinucleated giant glial cells in vitro.

The infectious disease melioidosis is caused by the bacterium Burkholderia pseudomallei. Melioidosis is characterised by high mortality and morbidity and can involve the central nervous system (CNS). We have previously discovered that B. pseudomallei can infect the CNS via the olfactory and trigemin...

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Bibliographic Details
Main Authors: Heidi Walkden, Ali Delbaz, Lynn Nazareth, Michael Batzloff, Todd Shelper, Ifor R Beacham, Anu Chacko, Megha Shah, Kenneth W Beagley, Johana Tello Velasquez, James A St John, Jenny A K Ekberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008017

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https://doi.org/10.1371/journal.pntd.0008017

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