Generation and Detection of Levuglandins and Isolevuglandins In Vitro and In Vivo

Levuglandins (LGs) and isolevuglandins (isoLGs), formed by rearrangement of endoperoxide intermediates generated through the cyclooxygenase and free radical induced oxidation of polyunsaturated fatty acids (PUFAs), are extraordinarily reactive, forming covalent adducts incorporating protein lysyl e-...

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Bibliographic Details
Main Authors: Tao Li, Wei Li, Ming Zhang
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/7/5333/