Hypermethylation of SOX2 Promoter in Endometrial Carcinogenesis

This paper aimed at investigating the expression and methylation profiles of SOX2, a gene coding for the stem cell-related transcription factor SOX2, in endometrial carcinomas. By methylation-specific polymerase chain reaction (MS-PCR), the methylation status of SOX2 promoter region in 72 endometria...

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Bibliographic Details
Main Authors: Oscar Gee-Wan Wong, Zhen Huo, Michelle Kwan-Yee Siu, HuiJuan Zhang, LiLi Jiang, Ester Shuk-Ying Wong, Annie Nga-Yin Cheung
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2010/682504