Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells
Persister cells are rare phenotypic variants that are able to survive antibiotic treatment. Unlike resistant bacteria, which have specific mechanisms to prevent antibiotics from binding to their targets, persisters evade antibiotic killing by entering a tolerant nongrowing state. Persisters have bee...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-09-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.01930-19 |