Raltegravir: molecular basis of its mechanism of action
<p>Abstract</p> <p>Integration of the HIV-1 viral DNA generated by reverse transcription of the RNA genome into the host cell chromosomes is a key step of viral replication, catalyzed by the viral integrase. In October 2007, the first integrase inhibitor, raltegravir, was approved...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-11-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | http://www.eurjmedres.com/content/14/S3/5 |