Asymmetrical Forces Dictate the Distribution and Morphology of Platelets in Blood Clots

Asymmetrical Forces Dictate the Distribution and Morphology of Platelets in Blood Clots

Primary hemostasis consists in the activation of platelets, which spread on the exposed extracellular matrix at the injured vessel surface. Secondary hemostasis, the coagulation cascade, generates a fibrin clot in which activated platelets and other blood cells get trapped. Active platelet-dependent...

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Bibliographic Details
Main Authors: Tatiana A. Kovalenko, Marie-Noelle Giraud, Anita Eckly, Anne-Sophie Ribba, Fabienne Proamer, Sandrine Fraboulet, Nadezhda A. Podoplelova, Jeremy Valentin, Mikhail A. Panteleev, Carmen Gonelle-Gispert, Stéphane Cook, Laurence Lafanechère, Anastasia N. Sveshnikova, Karin Sadoul
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
platelet
hemostasis
thrombosis
clot retraction
fibrin
computational modeling
Online Access:https://www.mdpi.com/2073-4409/10/3/584

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https://www.mdpi.com/2073-4409/10/3/584

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