Probing the SELEX process with next-generation sequencing.

Probing the SELEX process with next-generation sequencing.

<h4>Background</h4>SELEX is an iterative process in which highly diverse synthetic nucleic acid libraries are selected over many rounds to finally identify aptamers with desired properties. However, little is understood as how binders are enriched during the selection course. Next-genera...

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Bibliographic Details
Main Authors: Tatjana Schütze, Barbara Wilhelm, Nicole Greiner, Hannsjörg Braun, Franziska Peter, Mario Mörl, Volker A Erdmann, Hans Lehrach, Zoltán Konthur, Marcus Menger, Peter F Arndt, Jörn Glökler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22242135/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22242135/?tool=EBI

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