The Drosophila ortholog of the schizophrenia-associated CACNA1A and CACNA1B voltage-gated calcium channels regulate memory, sleep and circadian rhythms

The Drosophila ortholog of the schizophrenia-associated CACNA1A and CACNA1B voltage-gated calcium channels regulate memory, sleep and circadian rhythms

Schizophrenia exhibits up to 80% heritability. A number of genome wide association studies (GWAS) have repeatedly shown common variants in voltage-gated calcium (Cav) channel genes CACNA1C, CACNA1I and CACNA1G have a major contribution to the risk of the disease. More recently, studies using whole e...

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Bibliographic Details
Main Authors: Sergio Hidalgo, Jorge M. Campusano, James J.L. Hodge
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Neurobiology of Disease
Subjects:
Schizophrenia
CACNA1B
CACNA1A
Voltage-gated calcium channel
Cav2
Cacophony
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001431

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http://www.sciencedirect.com/science/article/pii/S0969996121001431

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