Pgrmc1: new roles in in the microglial mediation of progesterone-antagonism of estradiol-dependent neurite sprouting and in microglial activation

Pgrmc1 expression in microglia was recently shown by the present authors to mediate estrogen-progesterone interactions during axonal sprouting and to mediate microglial activation itself. We discuss these findings in relation to other functions of Pgrmc1 in the nervous system and its possible relat...

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Bibliographic Details
Main Authors: Namrata eBali, Todd E Morgan, Caleb E Finch
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Neuroscience
Subjects:
S2R
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00157/full