Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres

Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres

Biodegradable poly lactic-co-glycolic acid (PLGA) microspheres can be used to encapsulate peptide and offer a promising drug-delivery vehicle. In this work we investigate the dynamics of PLGA microspheres prepared by freeze-drying and the molecular mobility at lower temperatures leading to the glass...

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Bibliographic Details
Main Authors: Talia A. Shmool, Philippa J. Hooper, Gabriele S. Kaminski Schierle, Christopher F. van der Walle, J. Axel Zeitler
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Pharmaceutics
Subjects:
terahertz spectroscopy
microspheres
drug delivery
formulation development
PLGA
molecular mobility
Online Access:https://www.mdpi.com/1999-4923/11/6/291

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https://www.mdpi.com/1999-4923/11/6/291

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