Resistance to paclitaxel induces glycophenotype changes and mesenchymal-to-epithelial transition activation in the human prostate cancer cell line PC-3

The development of the multidrug resistance phenotype is one of the major challenges faced in the treatment of cancer. The multidrug resistance phenotype is characterized by cross-resistance to drugs with different chemical structures and mechanisms of action. In this work, we hypothesized that the...

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Bibliographic Details
Main Authors: Leonardo Marques da Fonseca, Danilo Macedo Calvalhan, Jose Osvaldo Previato, Lucia Mendonça Previato, Leonardo Freire-de-Lima
Format: Article
Language:English
Published: IOS Press 2020-09-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428320957506