Exchange of cytosolic content between T cells and tumor cells activates CD4 T cells and impedes cancer growth.

BACKGROUND:T cells are known to participate in the response to tumor cells and react with cytotoxicity and cytokine release. At the same time tumors established versatile mechanisms for silencing the immune responses. The interplay is far from being completely understood. In this study we show conta...

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Bibliographic Details
Main Authors: Matthias Hardtke-Wolenski, Lilli Kraus, Christel Schmetz, Britta Trautewig, Fatih Noyan, Florian W R Vondran, Hueseyin Bektas, Juergen Klempnauer, Elmar Jaeckel, Thorsten Lieke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3813479?pdf=render