Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark

Abstract Background Gametes are highly differentiated cells specialized to carry and protect the parental genetic information. During male germ cell maturation, histone proteins undergo distinct changes that result in a highly compacted chromatin organization. Technical difficulties exclude comprehe...

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Bibliographic Details
Main Authors: Marion Crespo, Lacey J. Luense, Marie Arlotto, Jialei Hu, Jean Dorsey, Encar García-Oliver, Parisha P. Shah, Delphine Pflieger, Shelley L. Berger, Jérôme Govin
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Epigenetics & Chromatin
Online Access:http://link.springer.com/article/10.1186/s13072-020-00349-5