The HER3 pathway as a potential target for inhibition in patients with biliary tract cancers.

INTRODUCTION:Expression of human epidermal growth factor receptor (HER)2 and HER3 have been investigated in small BTC studies using variable scoring systems. METHODS:HER2 and HER3 overexpression/amplification were explored following internationally agreed guidelines using immunohistochemistry (IHC)...

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Main Authors: Angela Lamarca, Salvatore Galdy, Jorge Barriuso, Sharzad Moghadam, Elizabeth Beckett, Jane Rogan, Alison Backen, Catherine Billington, Mairéad G McNamara, Richard A Hubner, Angela Cramer, Juan W Valle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6193702?pdf=render