Detection of Hematopoietic Stem Cell Transcriptome in Human Fetal Kidneys and Kidney Organoids Derived From Human Induced Pluripotent Stem Cells

Detection of Hematopoietic Stem Cell Transcriptome in Human Fetal Kidneys and Kidney Organoids Derived From Human Induced Pluripotent Stem Cells

BackgroundIn mammalians, hematopoietic stem cells (HSCs) arise in the dorsal aorta from the hemogenic endothelium, followed by their migration to the fetal liver and to the bone marrow. In zebrafish, the kidney is the site of primary hematopoiesis. In humans, the presence of HSCs in the fetal or adu...

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Bibliographic Details
Main Authors: Jin Wook Hwang, Christophe Desterke, Julien Loisel-Duwattez, Frank Griscelli, Annelise Bennaceur-Griscelli, Ali G. Turhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hematopoietic stem cell
fetal kidney
IPSC
organoid
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.668833/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.668833/full

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