RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies

RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies

Precision treatment of cancer requires knowledge on active tumor driving signal transduction pathways to select the optimal effective targeted treatment. Currently only a subset of patients derive clinical benefit from mutation based targeted treatment, due to intrinsic and acquired drug resistance...

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Bibliographic Details
Main Authors: Anja van de Stolpe, Wim Verhaegh, Jean-Yves Blay, Cynthia X. Ma, Patrick Pauwels, Mark Pegram, Hans Prenen, Dirk De Ruysscher, Nabil F. Saba, Susan F. Slovin, Karen Willard-Gallo, Hatim Husain
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
oncology precision medicine
treatment prediction
signaling pathway activity
mRNA profiling
low input analytes
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.598118/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.598118/full

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