Preparation and evaluation of injectable Rasagiline mesylate dual-controlled drug delivery system for the treatment of Parkinson’s disease

Preparation and evaluation of injectable Rasagiline mesylate dual-controlled drug delivery system for the treatment of Parkinson’s disease

A microsphere–gel in situ forming implant (MS–Gel ISFI) dual-controlled drug delivery system was applied to a high water-soluble small-molecule compound Rasagiline mesylate (RM) for effective treatment of Parkinson’s disease. This injectable complex depot system combined an in situ phase transition...

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Bibliographic Details
Main Authors: Ying Jiang, Xuemei Zhang, Hongjie Mu, Hongchen Hua, Dongyu Duan, Xiuju Yan, Yiyun Wang, Qingqing Meng, Xiaoyan Lu, Aiping Wang, Wanhui Liu, Youxin Li, Kaoxiang Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
sustained release
in situ forming implant
microspheres
water-soluble drug
mao-b inhibitor
Online Access:http://dx.doi.org/10.1080/10717544.2017.1419514

Internet

http://dx.doi.org/10.1080/10717544.2017.1419514

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