Analysis of Flagellin-Specific Adaptive Immunity Reveals Links to Dysbiosis in Patients With Inflammatory Bowel DiseaseSummary

Background & Aims: Bacterial flagellin is an important antigen in inflammatory bowel disease, but the role of flagellin-specific CD4+ T cells in disease pathogenesis remains unclear. Also unknown is how changes in intestinal microbiome intersect with those in microbiota-specific CD4+ T cells. We...

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Bibliographic Details
Main Authors: Laura Cook, Daniel J. Lisko, May Q. Wong, Rosa V. Garcia, Megan E. Himmel, Ernest G. Seidman, Brian Bressler, Megan K. Levings, Theodore S. Steiner
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19301675