Frequency-dependent gating of synaptic transmission and plasticity by dopamine

The neurotransmitter dopamine (DA) plays an important role in learning by enhancing the saliency of behaviorally relevant stimuli. How this stimulus selection is achieved on the cellular level, however, is not known. Here, in recordings from hippocampal slices, we show that DA acts specifically at t...

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Bibliographic Details
Main Authors: Hiroshi T Ito, Erin M Schuman
Format: Article
Language:English
Published: Frontiers Media S.A. 2007-11-01
Series:Frontiers in Neural Circuits
Subjects:
LTP
LTD
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.04.001.2007/full