Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells

Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells

Antithymocyte globulin (ATG) is used in the prevention of graft-versus-host disease during allogeneic hematopoietic stem cell transplantation. It is generally accepted that ATG mediates its immunosuppressive effect primarily via depletion of T cells. Here, we analyzed the impact of ATG-Fresenius (no...

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Bibliographic Details
Main Authors: Tobias Roider, Michael Katzfuß, Carina Matos, Katrin Singer, Kathrin Renner, Peter J. Oefner, Katja Dettmer-Wilde, Wolfgang Herr, Ernst Holler, Marina Kreutz, Katrin Peter
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
allogeneic hematopoietic stem cell transplantation
dendritic cell
antithymocyte globulin
Grafalon
tolerogenic
indoleamine 2,3-dioxygenase
immunosuppressive
Online Access:http://www.mdpi.com/1422-0067/17/12/2081

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http://www.mdpi.com/1422-0067/17/12/2081

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