Functional annotation by identification of local surface similarities: a novel tool for structural genomics

<p>Abstract</p> <p>Background</p> <p>Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus having different order and/or spacing in the sequence. Hence, func...

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Bibliographic Details
Main Authors: Zanzoni Andreas, Ausiello Gabriele, Ferrè Fabrizio, Helmer-Citterich Manuela
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/6/194