Developmental pattern of hepatic drug-metabolizing enzymes in pediatric population and its role in optimal drug treatment

Developmental pattern of hepatic drug-metabolizing enzymes in pediatric population and its role in optimal drug treatment

Pediatric pharmacokinetics (PK) and pharmacodynamics (PD) differ from adults in multiple aspects. The extrapolation of PK/PD data from adults to children is not always simple because children are not small adults. Differential development of metabolic enzymes in children affects both PK and PD of a...

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Bibliographic Details
Main Authors: Sunitha Kodidela, S Suresh Kumar, Chakradhara Rao Satyanarayana Uppugunduri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Archives of Medicine and Health Sciences
Subjects:
Adults
adverse drug reaction
children
dose
metabolism
ontogeny
pediatric population
pharmacokinetics
Online Access:http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2017;volume=5;issue=1;spage=115;epage=122;aulast=Kodidela

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http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2017;volume=5;issue=1;spage=115;epage=122;aulast=Kodidela

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