Enhancement of tumor tropism of mPEGylated nanoparticles by anti-mPEG bispecific antibody for ovarian cancer therapy

Abstract Ovarian cancer is highly metastatic, with a high frequency of relapse, and is the most fatal gynecologic malignancy in women worldwide. It is important to elevate the drug susceptibility and cytotoxicity of ovarian cancer cells, thereby eliminating resident cancer cells for more effective t...

Full description

Bibliographic Details
Main Authors: Wen-Wei Lin, Yi-An Cheng, Chia-Ching Li, Kai-Wen Ho, Huei-Jen Chen, I.-J.u Chen, Bo-Cheng Huang, Hui-Ju Liu, Yun-Chi Lu, Chiu-Min Cheng, Ming-Yii Huang, Hung-Wen Lai, Tian-Lu Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87271-2