Development of the Binary and Ternary Atorvastatin Solid Dispersions: In Vitro and In Vivo Investigations

The object of this study was to prepare binary and ternary solid dispersions of atorvastatin (ATR) by the melting method using PEGs and poloxamer 188 (P188) as the carriers, singly and in combination with each other. Dissolution behavior, solubility studies, X-ray diffractometry, differential scanni...

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Bibliographic Details
Main Authors: Elahe Faraji, Mojdeh Mohammadi, Mohammad Mehdi Mahboobian
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/6644630