Synthetic studies towards bottromycin

Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion. The intramolecular approach allows the synthesis o...

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Bibliographic Details
Main Authors: Stefanie Ackermann, Hans-Georg Lerchen, Dieter Häbich, Angelika Ullrich, Uli Kazmaier
Format: Article
Language:English
Published: Beilstein-Institut 2012-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.189