Exposure of Triclosan in Porcine Oocyte Leads to Superoxide Production and Mitochondrial-Mediated Apoptosis During In Vitro Maturation

Exposure of Triclosan in Porcine Oocyte Leads to Superoxide Production and Mitochondrial-Mediated Apoptosis During In Vitro Maturation

While triclosan (TCS) exerts detrimental effects on female reproduction, the effect of TCS-derived toxins on porcine oocytes during in vitro maturation (IVM) is unclear. This study investigated the effects of TCS on mitochondrion-derived reactive oxygen species (ROS) production and apoptosis pathway...

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Bibliographic Details
Main Authors: Hyo-Jin Park, Bong-Seok Song, Jin-Woo Kim, Seul-Gi Yang, Sun-Uk Kim, Deog-Bon Koo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
triclosan
superoxide
Mito-TEMPO
cumulus cell expansion
apoptosis
porcine oocyte maturation
Online Access:https://www.mdpi.com/1422-0067/21/9/3050

Internet

https://www.mdpi.com/1422-0067/21/9/3050

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