Vulnerabilities in Yersinia pestis caf operon are unveiled by a Salmonella vector.

During infection, Yersinia pestis uses its F1 capsule to enhance survival and cause virulence to mammalian host. Since F1 is produced in large quantities and secreted into the host tissues, it also serves as a major immune target. To hold this detrimental effect under proper control, Y. pestis expre...

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Bibliographic Details
Main Authors: Ling Cao, Timothy Lim, SangMu Jun, Theresa Thornburg, Recep Avci, Xinghong Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3340336?pdf=render