Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.

Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.

Evidence from mouse models suggests that zinc-α2-glycoprotein (ZAG) is a novel anti-obesity adipokine. In humans, however, data are controversial and its physiological role in adipose tissue (AT) remains unknown. Here we explored the molecular mechanisms by which ZAG regulates carbohydrate metabolis...

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Bibliographic Details
Main Authors: Victòria Ceperuelo-Mallafré, Miriam Ejarque, Xavier Duran, Gisela Pachón, Ana Vázquez-Carballo, Kelly Roche, Catalina Núñez-Roa, Lourdes Garrido-Sánchez, Francisco J Tinahones, Joan Vendrell, Sonia Fernández-Veledo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4465909?pdf=render

Internet

http://europepmc.org/articles/PMC4465909?pdf=render

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